This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories for identifying individuals through remains , and students of forensic science. The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis.
It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis. Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping.
Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level. Forensic DNA Analysis: Technological Development and Innovative Applications provides a fascinating overview of new and innovative technologies and current applications in forensic genetics.
Edited by two forensic experts with many years of forensic crime experience with the Italian police and with prestigious academic universities, the volume takes an interdisciplinary perspective, the volume presents an introduction to genome polymorphisms, discusses, forensic genetic markers, presents a variety of new methods and techniques in forensic genetics, and looks at a selection of new technological innovations and inventions now available from commercial vendors.
The book is an important resource for scientists, researchers, and other experts in the field who will find it of interest for its exhaustive discussion of the most important technological innovations in forensic genetics. For those newer to the field, the volume will be an invaluable reference guide to the forensic world.
The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting, yet for those with limited scientific knowledge, understanding DNA enough to utilize it properly can be a daunting task. Since its introduction in the late s, DNA analysis has revolutionized the forensic sciences: it has helped to convict the guilty, exonerate the wrongfully convicted, identify victims of mass atrocities, and reunite families whose members have been separated by war and repressive regimes.
Yet, many of the scientific, legal, societal, and ethical concepts that underpin forensic DNA analysis remain poorly understood, and their application often controversial. Told by over twenty experts in genetics, law, and social science, Silent Witness relates the history and development of modern DNA forensics and its application in both the courtroom and humanitarian settings.
By providing a critical inquiry into modern forensic DNA science, Silent Witness underscores the need to balance the benefits of using forensic genetics to solve crime with the democratic right to safeguard against privacy invasion and unwarranted government scrutiny, and raises the question of what it means to be an autonomous individual in a world where the most personal elements of one's identity are now publicly accessible.
DNA evidence is widely used in the modern justice system. Statistical methodology plays a key role in ensuring that this evidence is collected, interpreted, analysed and presented correctly.
This book is a guide to assessing DNA evidence and presenting that evidence in a courtroom setting. It offers practical guidance to forensic scientists with little dependence on mathematical ability, and provides the scientist with the understanding they require to apply the methods in their work.
Since the publication of the first edition of this book in there have been many incremental changes, and one dramatic change which is the emergence of low template DNA LTDNA profiles. The author's own open-source R code likeLTD is described and used for worked examples in the book. Commercial and free software are also covered. This book describes the basics and various applications of DNA fingerprinting, including in actual case studies.
Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems.
Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies. Covering a range of fundamental topics essential to modern forensic investigation, the fifth edition of the landmark text Forensic Science: An Introduction to Scientific and Investigative Techniques presents contributions and case studies from the personal files of experts in the field.
In the fully updated 5th edition, Bell combines these testimonies into an accurate and engrossing account of cutting edge of forensic science across many different areas. Designed for a single-term course at the undergraduate level, the book begins by discussing the intersection of law and forensic science, how things become evidence, and how courts decide if an item or testimony is admissible.
The text invites students to follow evidence all the way from the crime scene into laboratory analysis and even onto the autopsy table. Forensic Science offers the fullest breadth of subject matter of any forensic text available, including forensic anthropology, death investigation including entomology , bloodstain pattern analysis, firearms, tool marks, and forensic analysis of questioned documents.
Going beyond theory to application, this text incorporates the wisdom of forensic practitioners who discuss the real cases they have investigated. Textboxes in each chapter provide case studies, current events, and advice for career advancement. A brand-new feature, Myths in Forensic Science, highlights the differences between true forensics and popular media fictions. Each chapter begins with an overview and ends with a summary, and key terms, review questions, and up-to-date references.
Appropriate for any sensibility, more than full-color photos from real cases give students a true-to-life learning experience. Written by leaders in the fields of biology and statistics, including a contribution from Peter Gill, the father of DNA analysis, the book emphasizes the interpretation of test results and provides the necessary formulae in an easily accessible manner. This latest edition is fully updated and includes current and emerging techniques in this fast-moving field. George Carmody, a well-respected professor in forensic genetics.
Specific examples make the concepts of population genetics more understandable. This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories for identifying individuals through remains , and students of forensic science.
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. The volume addreses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility.
Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update--The Evaluation of Forensic DNA Evidence--provides the complete, up-to-date picture of this highly important and visible topic.
This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students. The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis.
The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis.
Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping.
Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level. A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level. This is the definitive source of information on techniques for the identification and sequencing of old DNA pieces and their use in biological and medical research and application.
Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches. What brings them together is the interest in specific methods of handling aDNA, i. This books serves as an ideal guideline for it demonstrates how problem-solving strategies can be applied in various areas. The book offers well-tested protocols for DNA quantification using real-time PCR on forensic samples and for the determination of the number of amelogenine gene copies.
For forensic geneticists, there are readily reproducible methods for species identification, ancient DNA, and pharmacogenetics. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts.
This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic tool--modifying some recommendations presented in the volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors particularly false matches can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero.
The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies.
This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticists--and helpful to attorneys, judges, and others who need to understand DNA and the law.
Anyone working in laboratories and in the courts or anyone studying this issue should own this book. Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application.
Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community.
The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs.
While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
The book presents hands-on protocols for conventional and advanced forensic DNA fingerprinting experiments. It includes manual, semi-automatic, and advanced automatic techniques for DNA extraction from different biological samples. It also discusses various qualitative and quantitative approaches for the assessment of extracted forensic DNA. It contains protocols for the amplification of short tandem repeat markers STRs for the amplification-based target enrichment of the forensic samples.
Capillary Electrophoresis Chapter 7. Quality Assurance and Validation Chapter 8. DNA Databases Chapter 9. Degraded DNA Chapter Single Nucleotide Polymorphisms and Applications Chapter X-Chromosome Analysis Chapter Non-human DNA Chapter New Technologies and Automation Chapter Powered by.
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